Tuberculosis or TB, caused by Mycobacterium tuberculosis is one of the diseases with a high fatality rate. The disease spreads when an infected person spits, coughs or sneezes, dispersing the bacteria in the air. Due to the slow growth pattern and multi-drug resistance of Mycobacterium tuberculosis, the disease presents a major challenge in terms of treatment and quick diagnostic techniques. Tuberculosis- Whole Genome Sequencing is a high sensitivity technique that covers 18 antibiotic resistance profiles with a turnaround time of 12 days. It aids in detecting co-infection and mixed infection as well as helps in strain identification. It helps in the early detection of infection for better-individualized treatment with correct antibiotics at the right time.The TB-WGS test is suggested to individuals with symptoms like - cough for more than three weeks, chills, fever, night sweats, loss of appetite, weakness, weight loss.